{"id":9,"date":"2021-11-10T20:43:49","date_gmt":"2021-11-10T20:43:49","guid":{"rendered":"https:\/\/faculty.cortland.edu\/wolf\/?page_id=9"},"modified":"2026-09-06T12:53:51","modified_gmt":"2026-09-06T16:53:51","slug":"home","status":"publish","type":"page","link":"https:\/\/faculty.cortland.edu\/wolf\/","title":{"rendered":"Home"},"content":{"rendered":"<h1>Glass Chemistry at SUNY Cortland<\/h1>\n<p>Glasses, formed when a liquid becomes kinetically trapped in an amorphous, solid-like state upon sufficiently rapid cooling, are of significant importance in fields ranging from organic electronics to coatings to pharmaceuticals. This is generally a consequence of their amorphous structure which allow glasses to, for example, be easily dissolved for pharmaceutical applications. However, the out-of-equilibrium nature of glasses does pose challenges, in particular that a glass may change over time in seeking a state closer to equilibrium. The Wolf lab works to develop strategies to improve crystallization resistance and other origins of instability under consideration in pharmaceutical glass storage. We use methods including spin-coating, and melt-quenching to prepare glasses and compare their properties using microscopy, differential scanning calorimetry, powder X-ray diffraction, and other tools.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-61\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans-300x137.png\" alt=\"Graph of Entropy, Volume, or Enthalpy vs Temperature showing crystallization or supercooling\/glass transition of liquid on cooling\" width=\"657\" height=\"300\" srcset=\"https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans-300x137.png 300w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans-768x350.png 768w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans.png 1023w\" sizes=\"auto, (max-width: 657px) 100vw, 657px\" \/><\/p>\n<hr \/>\n<h2><strong>Current Projects<\/strong><\/h2>\n<h3><em><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-202 size-medium\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2026\/09\/Aging-300x215.png\" alt=\"\" width=\"300\" height=\"215\" srcset=\"https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2026\/09\/Aging-300x215.png 300w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2026\/09\/Aging.png 483w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>Behavior of Amorphous Pharmaceuticals in the Presence of Polymer<\/em><\/h3>\n<p>We are preparing amorphous pharmaceuticals in the presences of very small amounts of polymer to study properties including crystallization, liquid fragility, glass transition, physical ageing and others.<\/p>\n<h3><\/h3>\n<h3><\/h3>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3><em><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-203 alignright\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2026\/09\/CaRI.png\" alt=\"\" width=\"304\" height=\"172\" \/>Confinement of Amorphous Pharmaceuticals in Thin Films and Nanoparticle Packings<\/em><\/h3>\n<p>We are spin-coating thin films and of molecular glassformers and infiltrating molecular glassformers into nanoparticle layers to investigate the effect on confinement on crystallization.<\/p>\n<h3><\/h3>\n<h3><\/h3>\n<hr \/>\n<h3><\/h3>\n<h3><em>Effects of Processing on Crystallization Behavior<\/em><\/h3>\n<p>We are exploring the effect of processing conditions (including melting temperatures and cooling rates, as well as storage conditions and heat\/cool cycles) on crystallization of amorphous drugs.<\/p>\n<p>&nbsp;<\/p>\n<p><em>The views and opinions expressed in this<br \/>\npage are strictly those of the page author. The contents of this linked page have<br \/>\nnot been reviewed or approved by SUNY Cortland.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glass Chemistry at SUNY Cortland Glasses, formed when a liquid becomes kinetically trapped in an amorphous, solid-like state upon sufficiently rapid cooling, are of significant importance in fields ranging from organic electronics to coatings to pharmaceuticals. This is generally a consequence of their amorphous structure which allow glasses to, for example, be easily dissolved for [&hellip;]<\/p>\n","protected":false},"author":23,"featured_media":58,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"class_list":["post-9","page","type-page","status-publish","has-post-thumbnail","entry"],"_links":{"self":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":0,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/media\/58"}],"wp:attachment":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}