{"id":9,"date":"2021-11-10T20:43:49","date_gmt":"2021-11-10T20:43:49","guid":{"rendered":"https:\/\/faculty.cortland.edu\/wolf\/?page_id=9"},"modified":"2025-11-25T13:58:14","modified_gmt":"2025-11-25T18:58:14","slug":"home","status":"publish","type":"page","link":"https:\/\/faculty.cortland.edu\/wolf\/","title":{"rendered":"Home"},"content":{"rendered":"<h1>Glass Chemistry at SUNY Cortland<\/h1>\n<p>Glasses, formed when a liquid becomes kinetically trapped in an amorphous, solid-like state upon sufficiently rapid cooling, are of significant importance in fields ranging from organic electronics to coatings to pharmaceuticals. This is generally a consequence of their amorphous structure which allow glasses to, for example, be easily dissolved for pharmaceutical applications. However, the out-of-equilibrium nature of glasses does pose challenges, in particular that a glass may change over time in seeking a state closer to equilibrium. The Wolf lab works to develop strategies to improve crystallization resistance and other origins of instability under consideration in pharmaceutical glass storage. We use methods including spin-coating, and melt-quenching to prepare glasses and compare their properties using microscopy, differential scanning calorimetry, powder X-ray diffraction, and other tools.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-61\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans-300x137.png\" alt=\"Graph of Entropy, Volume, or Enthalpy vs Temperature showing crystallization or supercooling\/glass transition of liquid on cooling\" width=\"657\" height=\"300\" srcset=\"https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans-300x137.png 300w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans-768x350.png 768w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/03\/trans.png 1023w\" sizes=\"auto, (max-width: 657px) 100vw, 657px\" \/><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-106\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230616115809039_IMC3_DCM_nucl65_90deg_1158-300x169.png\" alt=\"Crystals forming on IMC glassy film, viewed under polarized light\" width=\"701\" height=\"395\" srcset=\"https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230616115809039_IMC3_DCM_nucl65_90deg_1158-300x169.png 300w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230616115809039_IMC3_DCM_nucl65_90deg_1158-1024x576.png 1024w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230616115809039_IMC3_DCM_nucl65_90deg_1158-768x432.png 768w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230616115809039_IMC3_DCM_nucl65_90deg_1158-1536x864.png 1536w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230616115809039_IMC3_DCM_nucl65_90deg_1158.png 1882w\" sizes=\"auto, (max-width: 701px) 100vw, 701px\" \/><\/p>\n<h2><strong>Current Projects<\/strong><\/h2>\n<h3><em>Synthesis of<\/em><em>\u00a0Novel Glassformers<\/em><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-148\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2024\/09\/20240603_144220-300x225.jpg\" alt=\"Chemistry glassware with orange liquid\" width=\"208\" height=\"156\" srcset=\"https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2024\/09\/20240603_144220-300x225.jpg 300w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2024\/09\/20240603_144220-1024x768.jpg 1024w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2024\/09\/20240603_144220-768x576.jpg 768w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2024\/09\/20240603_144220-1536x1152.jpg 1536w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2024\/09\/20240603_144220-2048x1536.jpg 2048w\" sizes=\"auto, (max-width: 208px) 100vw, 208px\" \/><\/strong><\/h3>\n<p>We are working to prepare novel glassformers, based on a well-studied class of glassformers, to probe the impact of hydrogen bonding and rotational barriers on glassy properties.<\/p>\n<p>&nbsp;<\/p>\n<h3><em>Behavior of Amorphous Pharmaceuticals in the Presence of Polymer<\/em><\/h3>\n<p>We are preparing indomethacin in the presences of very small amounts of polymer (PEO and PVP) to study properties including crystallization, liquid fragility, glass transition, and others.<\/p>\n<h3><em>Confinement of Amorphous Pharmaceuticals in Thin Films and Nanoparticle Packings<\/em><\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-103 size-medium\" src=\"http:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230620135748026_IMC_mq_surf__90_1357-300x169.jpg\" alt=\"Crystallizing glass IMC viewed under polarized light\" width=\"300\" height=\"169\" srcset=\"https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230620135748026_IMC_mq_surf__90_1357-300x169.jpg 300w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230620135748026_IMC_mq_surf__90_1357-1024x576.jpg 1024w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230620135748026_IMC_mq_surf__90_1357-768x432.jpg 768w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230620135748026_IMC_mq_surf__90_1357-1536x864.jpg 1536w, https:\/\/faculty.cortland.edu\/wolf\/wp-content\/uploads\/sites\/59\/2023\/06\/20230620135748026_IMC_mq_surf__90_1357-2048x1152.jpg 2048w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>We are spin-coating thin films and of molecular glassformers and infiltrating molecular glassformers into nanoparticle layers to investigate the effect on confinement on crystallization.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h3><em>Effects of Processing on Crystallization Behavior<\/em><\/h3>\n<p>We are exploring the effect of processing conditions (including melting temperatures and cooling rates, as well as storage conditions and heat\/cool cycles) on crystallization of amorphous griseofulvin.<\/p>\n<p>&nbsp;<\/p>\n<p><em>The views and opinions expressed in this<br \/>\npage are strictly those of the page author. The contents of this linked page have<br \/>\nnot been reviewed or approved by SUNY Cortland.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Glass Chemistry at SUNY Cortland Glasses, formed when a liquid becomes kinetically trapped in an amorphous, solid-like state upon sufficiently rapid cooling, are of significant importance in fields ranging from organic electronics to coatings to pharmaceuticals. This is generally a consequence of their amorphous structure which allow glasses to, for example, be easily dissolved for [&hellip;]<\/p>\n","protected":false},"author":23,"featured_media":58,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"class_list":["post-9","page","type-page","status-publish","has-post-thumbnail","entry"],"_links":{"self":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":0,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/media\/58"}],"wp:attachment":[{"href":"https:\/\/faculty.cortland.edu\/wolf\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}